BDBM50413784 UROTENSIN-II

SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O

InChI Key InChIKey=HFNHAPQMXICKCF-ZYNSIFMHSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50413784   

TargetUrotensin-2 receptor(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50413784(UROTENSIN-II)
Affinity DataKi:  0.794nMAssay Description:Displacement of [125I]urotensin-2 from human recombinant UT receptor expressed in CHO-K1 cells by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(Homo sapiens (Human))
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50413784(UROTENSIN-II)
Affinity DataEC50:  4.10nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(RAT)
University Of Naples&Quot;Federico Ii&Quot

Curated by ChEMBL
LigandPNGBDBM50413784(UROTENSIN-II)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at UT receptor in rat aorta assessed as contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed