BDBM50414973 CHEMBL572537

SMILES O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1

InChI Key InChIKey=IZCXWLUHLXSGCA-UHFFFAOYSA-N

Data  2 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50414973   

TargetC-C chemokine receptor type 8(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50414973(CHEMBL572537)
Show SMILES O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1
Show InChI InChI=1S/C24H29N3O2/c28-23(20-4-11-25-12-5-20)27-15-9-24(10-16-27)7-13-26(14-8-24)18-21-3-1-2-19-6-17-29-22(19)21/h1-5,11-12H,6-10,13-18H2
Affinity DataIC50: 1.48E+3nMAssay Description:Antagonist activity at human CCR8More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50414973(CHEMBL572537)
Show SMILES O=C(N1CCC2(CCN(Cc3cccc4CCOc34)CC2)CC1)c1ccncc1
Show InChI InChI=1S/C24H29N3O2/c28-23(20-4-11-25-12-5-20)27-15-9-24(10-16-27)7-13-26(14-8-24)18-21-3-1-2-19-6-17-29-22(19)21/h1-5,11-12H,6-10,13-18H2
Affinity DataIC50: 7.76E+3nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair