BDBM50415761 CHEMBL5285102

SMILES CCc1ccc(cc1)N(C1CCC1)S(=O)(=O)c1ccc2OC(CC(O)c2c1)C1CCOCC1

InChI Key InChIKey=NIQAXHRTVPHVOC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50415761   

TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50: 5nMAssay Description:Displacement of BODIPY from APC-labelled human RORgammat LBD incubated for 15 mins by by LANCE detection analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50: 10nMAssay Description:Inhibition of RORgammat in human Jurkat cells assessed as inhibition of RORgammat transcriptional activity incubated for 10 mins by luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50: 42nMAssay Description:Inhibition of human GAL4-fused RORgammat LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-alpha(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50: 8.54E+3nMAssay Description:Inhibition of human GAL4-fused RORalpha LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNuclear receptor ROR-beta(Human)
Jiangsu Carefree Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50415761(CHEMBL5285102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GAL4-fused RORbeta LBD transfected in HEK293T cell measured for 16 to 20 hrs by by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed