BDBM50417989 CHEMBL1672422::US11414402, Example 7

SMILES O=S(=O)(N[C@@H]1CCN(C1)C#N)c1ccccc1

InChI Key InChIKey=FXILBKWGQQHVJE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50417989   

TargetCathepsin K(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50417989(CHEMBL1672422 | US11414402, Example 7)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant cathepsin K after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50417989(CHEMBL1672422 | US11414402, Example 7)
Affinity DataIC50: 316nMAssay Description:Inhibition of human recombinant cathepsin C after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50417989(CHEMBL1672422 | US11414402, Example 7)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human recombinant cathepsin S after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM50417989(CHEMBL1672422 | US11414402, Example 7)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetCathepsin B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50417989(CHEMBL1672422 | US11414402, Example 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant cathepsin B after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed