BDBM504270 N-[2-[(2R)-2-Fluoro-3-hydroxy- 3-methyl-butyl]-6-(oxetan-3-yl)- 1-oxo-isoindolin-5- yl]pyrazolo[1,5-a]pyrimidine-3- carboxamide::US11034698, Example 147

SMILES CC(C)(O)[C@H](F)CN1Cc2cc(NC(=O)c3cnn4cccnc34)c(cc2C1=O)C1COC1

InChI Key InChIKey=JKNQKOBXTDDTDM-LJQANCHMSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504270   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM504270(N-[2-[(2R)-2-Fluoro-3-hydroxy- 3-methyl-butyl]-6-(...)
Affinity DataKi:  48nMAssay Description:The IRAK4 reaction conditions were optimized using an IRAK1-derived peptide (sequence H-KKARFSRFAGSSPSQSSMVAR) to provide a linear reaction rate over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent