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BDBM504311 3α,7α,11β-trihydroxy-6α-ethyl-23-(1,2,4-oxadiazol-5-oxo-3-yl)-23-nor-5β-cholane ::US11034717, Compound 7

SMILES: CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12

InChI Key:

Data: 5 EC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 504311   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fragile X mental retardation syndrome-related protein 1


(Human)
BDBM504311
PNG
(3α,7α,11β-trihydroxy-6α-ethyl-...)
Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 29n/an/an/an/a



Intercept Pharmaceuticals, Inc.

US Patent


Assay Description
AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...


US Patent US11034717 (2021)

More data for this
Ligand-Target Pair
Fragile X mental retardation syndrome-related protein 1


(Human)
BDBM504311
PNG
(3α,7α,11β-trihydroxy-6α-ethyl-...)
Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 29n/an/an/an/a



Intercept Pharmaceuticals, Inc.

US Patent


Assay Description
AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...


US Patent US11034717 (2021)

More data for this
Ligand-Target Pair
FMR1 autosomal homolog 1


(Dog)
BDBM504311
PNG
(3α,7α,11β-trihydroxy-6α-ethyl-...)
Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
PDB

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 700n/an/an/an/a



Intercept Pharmaceuticals, Inc.

US Patent


Assay Description
AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...


US Patent US11034717 (2021)

More data for this
Ligand-Target Pair
Fragile X mental retardation syndrome-related protein 1


(Rat)
BDBM504311
PNG
(3α,7α,11β-trihydroxy-6α-ethyl-...)
Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 200n/an/an/an/a



Intercept Pharmaceuticals, Inc.

US Patent


Assay Description
AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...


US Patent US11034717 (2021)

More data for this
Ligand-Target Pair
Fragile X mental retardation syndrome-related protein 1


(Mouse)
BDBM504311
PNG
(3α,7α,11β-trihydroxy-6α-ethyl-...)
Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 210n/an/an/an/a



Intercept Pharmaceuticals, Inc.

US Patent


Assay Description
AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...


US Patent US11034717 (2021)

More data for this
Ligand-Target Pair