BDBM50431107 CHEMBL2332052
SMILES CC(=S)NCCC1CCN(CC1)c1ncnc2cc(sc12)C(N)=O
InChI Key InChIKey=TZDSTEUXHBSJJN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50431107
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Sirtris A Gsk
Curated by ChEMBL
Sirtris A Gsk
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human His-tagged SIRT3 (102 to 399) expressed in Escherichia coli BL21(DE3) assessed as inhibition of deacetylation of Ac-RHKKAcW-NH2 s...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged SIRT1 (1 to 747) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate preincubated for 20 mins measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of His-tagged SIRT2 (1 to 389) (unknown origin)-mediated deacetylation of Ac-RHKKAcW-NH2 substrate incubated for 20 mins prior to substrat...More data for this Ligand-Target Pair