BDBM50433375 CHEMBL472879::GNF-Pf-359
SMILES Cc1nc(nc(NCCc2ccccc2)c1Cl)-c1ccccn1
InChI Key InChIKey=HIUOABSWQSUEGK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50433375
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Co2+More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 710nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Zn2+More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1 in presence of Mn2+More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HuMetAP2 using Met-Pro-pNA as substrate by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of HuMetAP1 using Met-Pro-pNA as substrate by spectrophotometer based analysisMore data for this Ligand-Target Pair
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair