BDBM50434371 AZURE A::Azure A (12)

SMILES C[N+](C)=c1ccc2nc3ccc(N)cc3sc2c1

InChI Key InChIKey=HMYISFASHDWPMO-UHFFFAOYSA-O

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434371   

TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University

LigandPNGBDBM50434371(AZURE A | Azure A (12))
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£t zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434371(AZURE A | Azure A (12))
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant brain tau protein (412 amino acid residues) filament assembly expressed in Escherichia coli BL21(DE3) by electron mic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Humboldt Universit£t zu Berlin

Curated by ChEMBL
LigandPNGBDBM50434371(AZURE A | Azure A (12))
Affinity DataIC50:  69nMAssay Description:Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed