BDBM50436006 CHEMBL2392171

SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1

InChI Key InChIKey=SARVDTIHXSLJDV-UHFFFAOYSA-N

Data  1 KI  4 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50436006   

TargetG-protein coupled receptor 35(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436006(CHEMBL2392171)
Show SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1
Show InChI InChI=1S/C17H8BrCl2NO5/c18-7-3-10-13(22)6-14(17(24)25)26-15(10)12(4-7)21-16(23)9-2-1-8(19)5-11(9)20/h1-6H,(H,21,23)(H,24,25)
Affinity DataKi:  0.938nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436006(CHEMBL2392171)
Show SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1
Show InChI InChI=1S/C17H8BrCl2NO5/c18-7-3-10-13(22)6-14(17(24)25)26-15(10)12(4-7)21-16(23)9-2-1-8(19)5-11(9)20/h1-6H,(H,21,23)(H,24,25)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436006(CHEMBL2392171)
Show SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1
Show InChI InChI=1S/C17H8BrCl2NO5/c18-7-3-10-13(22)6-14(17(24)25)26-15(10)12(4-7)21-16(23)9-2-1-8(19)5-11(9)20/h1-6H,(H,21,23)(H,24,25)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase report...More data for this Ligand-Target Pair
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436006(CHEMBL2392171)
Show SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1
Show InChI InChI=1S/C17H8BrCl2NO5/c18-7-3-10-13(22)6-14(17(24)25)26-15(10)12(4-7)21-16(23)9-2-1-8(19)5-11(9)20/h1-6H,(H,21,23)(H,24,25)
Affinity DataEC50:  5.54nMAssay Description:Agonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment as...Checked by AuthorMore data for this Ligand-Target Pair
TargetG-protein coupled receptor 35(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50436006(CHEMBL2392171)
Show SMILES OC(=O)c1cc(=O)c2cc(Br)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1
Show InChI InChI=1S/C17H8BrCl2NO5/c18-7-3-10-13(22)6-14(17(24)25)26-15(10)12(4-7)21-16(23)9-2-1-8(19)5-11(9)20/h1-6H,(H,21,23)(H,24,25)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair