BDBM50436220 CHEMBL49563

SMILES Cc1c(c2c(c(c1O)C)CC[C@](O2)(C)CCC[C@@H](C)CCC[C@@H](C)CCCC(C)C)C

InChI Key InChIKey=GVJHHUAWPYXKBD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50436220   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50436220(CHEMBL49563)
Affinity DataEC50: >1.00E+5nMAssay Description:Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as increase in amyloid beta 38 genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50436220(CHEMBL49563)
Affinity DataIC50: 1.00E+5nMAssay Description:Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as decrease in amyloid beta 42 genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50436220(CHEMBL49563)
Affinity DataIC50: 1.00E+5nMAssay Description:Modulation of human gamma-secretase presenilin-1 subunit expressed in CHO cells coexpressing human APP assessed as decrease in amyloid beta 40 genera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed