BDBM50445952 CHEMBL3105886

SMILES NC(=O)n1ccc2ccc(nc12)-c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=HIBOPBGHLVWFCH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445952   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50445952(CHEMBL3105886)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human GST-fused PARP-1 expressed in Escherichia coli after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50445952(CHEMBL3105886)
Affinity DataEC50:  400nMAssay Description:Inhibition of PARP-1 in human HeLa cells assessed as decrease of H2O2-induced PARylation after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed