BDBM50446685 CHEMBL3113613

SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=VGSKHFCMGREMKD-RUZDIDTESA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50446685   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446685(CHEMBL3113613)
Affinity DataKi:  37nMAssay Description:Inhibition of 5-LOX (unknown origin) by UV-Vis spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446685(CHEMBL3113613)
Affinity DataIC50:  52nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50446685(CHEMBL3113613)
Affinity DataIC50:  14nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate after 5 mins by EIA in presence of pig liver esteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed