BDBM504510 2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin- 3-yl}-N-(2-methylpiperidin-3- yl)pyrimidine-5-carboxamide, trifluoroacetate salt, mixture of stereoisomers::US11065249, Example 23::US11471458, Example 23::US20230405002, Example 23

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC1CCCNC1C

InChI Key InChIKey=WMDXJXBYYYGMAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 504510   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504510(2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin- 3-yl}-N-(...)
Affinity DataIC50:  1.40E+4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504510(2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin- 3-yl}-N-(...)
Affinity DataIC50:  1.40E+4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM504510(2-{5-[(3-ethoxypyridin-2-yl)oxy]pyridin- 3-yl}-N-(...)
Affinity DataIC50:  1.40E+4nMAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white polypropylene plates (Nunc) in a total volume of 20 μL. To 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent