BDBM50452723 CHEMBL1518160

SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccco1)c1c(O)nc2ccc(Cl)cc2c1-c1ccccc1

InChI Key InChIKey=XQGHSLYQBZDYJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452723   

TargetGlycogen synthase kinase-3 alpha(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50452723(CHEMBL1518160)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human GSK-3alpha S449A mutant (2 to end residues) using phospho GS2 peptide as substrate after 40 mins in presence of [gamma-33ATP] by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50452723(CHEMBL1518160)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of human GSK-3beta using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE substrate peptide and [gamma-33P-ATP] incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed