BDBM50452830 CHEMBL4203092

SMILES CCCCN1CCC(CC1)c1c(C)nc2c(OCc3ccccc3C)cccn12

InChI Key InChIKey=AJSRKNNYCYTYRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50452830   

TargetPresenilin-1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50452830(CHEMBL4203092)
Affinity DataIC50: 8.70E+3nMAssay Description:Modulatory activity against gamma-secretase in human SK-N-BE(2) cells assessed as reduction in amyloid beta 42 production after 6 hrs by sandwich ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed