BDBM50454184 CHEMBL4205015

SMILES CC(C)c1n[nH]c2c(NCc3ccccc3)nc(NC3CCC(N)CC3)nc12

InChI Key InChIKey=XGFAWOAQXUCOCE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50454184   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK4 (S4 to E303 residues)/CyclinD1 (Q4 to I295 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK6 (M1 to A326 residues)/CyclinD1 (Q4 to I295 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK9 (M1 to F372 residues)/N-terminal His6-tagged CyclinT1 (M1 to K726 residue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK7 (M1 to F346 residues)/N-terminal His6-tagged CyclinH (M1 to L323 residues...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK5 (M1 to P292 residues)/N-terminal His6-tagged p25NCK (A104 to R307 residue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged CDK1 (M1 to M297 residues)/CyclinB1 (M1 to V433 residues) expressed in Sf9 insect cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454184(CHEMBL4205015)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to M298 residues)/CyclinA2 (M1 to V432 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed