BDBM50455384 CHEMBL4206423

SMILES COc1cc2CCN(Cc2cc1OC1CCCC1)S(=O)(=O)c1ccc(NC(C)=O)cc1

InChI Key InChIKey=MATVLUWHSFXXRL-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50455384   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 950nMAssay Description:Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE10A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE8A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE11AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
South China Agricultural University

Curated by ChEMBL
LigandPNGBDBM50455384(CHEMBL4206423)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed