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BDBM50455966 CHEMBL39621

SMILES: OC(=O)\C=C\C(O)=O.CC(C)COc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C

InChI Key: InChIKey=FRIMIDMIUYRBFG-WLHGVMLRSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455966   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50455966
PNG
(CHEMBL39621)
Show SMILES CC(C)COc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C
Show InChI InChI=1S/C20H29N3O3.C4H4O4/c1-13(2)12-26-18-7-5-4-6-17(18)19(24)22-20(25)21-14-10-15-8-9-16(11-14)23(15)3;5-3(6)1-2-4(7)8/h4-7,13-16H,8-12H2,1-3H3,(H2,21,22,24,25);1-2H,(H,5,6)(H,7,8)/b;2-1+
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.20n/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.


J Med Chem 35: 1515-20 (1992)


Article DOI: 10.1021/jm00087a003
BindingDB Entry DOI: 10.7270/Q24B32SK
More data for this
Ligand-Target Pair