BDBM50458601 CHEMBL4217959::US10752615, Compound 138

SMILES: Nc1nccc(n1)-c1ccc(s1)C(=O)Nc1nc2ccccc2n1[C@H]1C[C@]2(C1)CCN(C2)C(=O)C=C

InChI Key: InChIKey=XGOJEPJETCHLMD-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50458601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase TXK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase TXK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM50458601 (CHEMBL4217959 | US10752615, Compound 138) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair