BDBM50463510 CHEMBL4244382
SMILES O=c1n(cnc2ccc(cc12)-c1ccnc2ccccc12)-c1ccc(cc1)N1CCOCC1
InChI Key InChIKey=MTDJGYWCNQTZLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50463510
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 54nMAssay Description:Binding affinity to partial length human KIT (I571 to D952 residues) expressed in bacterial expression system by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.90E+4nMAssay Description:Binding affinity to human ALK5 by KdELECT assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 250nMAssay Description:Binding affinity to partial length human PDGFRB (V582 to Y1009 residues) expressed in bacterial expression system by KdELECT assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Binding affinity to partial length human PDGFRA (V575 to D1002 residues) expressed in mammalian expression system by KdELECT assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 610nMAssay Description:Binding affinity to human ALK3 by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10E+4nMAssay Description:Binding affinity to human ALK4 by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataKd: 330nMAssay Description:Binding affinity to human ALK2 by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant GST-tagged human ALK2 catalytic domain (145 to 509 residues) expressed in Baculovirus expression system by FRET-based Lanth...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 420nMAssay Description:Binding affinity to human ALK1 by KdELECT assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 96nMAssay Description:Binding affinity to human ALK6 by KdELECT assayMore data for this Ligand-Target Pair