BDBM50466858 CHEMBL4292553

SMILES Oc1ccc(cc1O)-c1cnc2[nH]cc(-c3ccc(F)cc3)c2c1

InChI Key InChIKey=IRJDHVRCNAUAOH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50466858   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat recombinant 6His-tagged DYRK1A (1 to 502 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) using KISGRLSPIMTEQ as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataKd: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  570nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  1.99E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  890nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  9.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  57nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  3.35E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50: >1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  180nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  48nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataKd:  100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataKd:  71nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50466858(CHEMBL4292553)
Affinity DataIC50:  21nMAssay Description:Inhibition of 6xHis-tagged rat DYRK1A (1 to 502 residues) expressed in Escherichia coli BL21(DE3) using FKHR as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed