BDBM50485952 CHEMBL2180361

SMILES COc1cc(\C=C2/CCCN3C(=O)CON=C23)ccc1-n1cnc(C)c1

InChI Key InChIKey=OUGPFPUBTIPZKQ-OVCLIPMQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485952   

TargetPresenilin-1(Homo sapiens (Human))
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50485952(CHEMBL2180361)
Affinity DataIC50:  2.50E+3nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed