BDBM505045 2-[({5-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3- yl]pyridin- 2-yl} methyl) amino] pyridine- 4-carbox- amide::US11066396, Example 442
SMILES NC(=O)c1ccnc(NCc2ccc(cn2)-c2noc(n2)C(F)(F)F)c1
InChI Key InChIKey=NRBAVBGZDITUNV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 505045
Affinity DataIC50: 7.30nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:HDAC8 reagents: HDAC8 was purchased from Enzo Life Sciences [catalog #BML-SE145]. Assays were performed with buffer containing 20 mM HEPES, pH 8.0 [B...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair