BDBM50511917 CHEMBL4534834

SMILES Cc1ccc(c(C)c1)S(=O)(=O)NC(=O)COc1ccc2ccccc2c1

InChI Key InChIKey=KCRXXSQZEZOCFM-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511917   

TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50511917(CHEMBL4534834)
Affinity DataIC50:  9.20E+3nMAssay Description:Binding affinity to GST-tagged recombinant EPAC1 CNBD (169 to 318 residues) (unknown origin) expressed in Escherichia coli BL21 Star (DE3) incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50511917(CHEMBL4534834)
Affinity DataKd:  4.90E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 L273W mutant expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP based competitiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRap guanine nucleotide exchange factor 3(Homo sapiens (Human))
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50511917(CHEMBL4534834)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to GST-tagged human EPAC1 CNBD (149 to 318 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by 8-NBD-cAMP ba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed