BDBM50517781 CHEMBL4582553

SMILES COc1ncc(cc1C)N1CCc2ncnc(c2C1)-c1ccc(NCC2CCOCC2)nc1

InChI Key InChIKey=BPSGDTCNRHWJQU-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517781   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50517781(CHEMBL4582553)Copy SMILESCopy InChI

Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human PI3Kdelta using PIP2 as substrate after 35 to 40 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50517781(CHEMBL4582553)Copy SMILESCopy InChI

Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human PI3Kalpha using phosphatidyl inositol as substrate after 3 hrs by Kinase-Glo Plus reagent-based luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/22/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL