BDBM50520627 CHEMBL4536031

SMILES COc1cc(Cl)c(C(=O)N[C@@H](CN[C@H]2CC[C@@H](N)CC2)Cc2ccc(C#N)cc2)cc1-c1ccc(CN[C@H](C)c2ccc(C)cc2)o1

InChI Key InChIKey=BSISGUIVBKDTQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520627   

TargetATPase family AAA domain-containing protein 2B(Human)
University of Vermont

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520627BDBM50520627(CHEMBL4536031)
Affinity DataIC50: 20nMAssay Description:Displacement of tetra-acetylated H4 peptide from ATAD2B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520627BDBM50520627(CHEMBL4536031)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal Hexahistidine-GST-tagged human ATAD2 bromodomain expressed in Escherichia coli BL21 (DE3) Rosetta cells incubated for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520627BDBM50520627(CHEMBL4536031)
Affinity DataIC50: 166nMAssay Description:Induction of ATAD2 bromodomain (unknown origin) dimerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed