BDBM50529264 CHEMBL4513418

SMILES COc1ncc(cn1)-c1nc(C(=O)NC(N)=N)c(N)nc1N

InChI Key InChIKey=XFGYFQDKMRBURI-UHFFFAOYSA-N

Data  3 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50529264   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529264(CHEMBL4513418)
Affinity DataKi:  204nMAssay Description:Inhibition of human kidney uPA using fluorogenic Z-Pyr-Gly-Arg-MCA as substrate measured after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetUrokinase-type plasminogen activator(Homo sapiens)
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529264(CHEMBL4513418)
Affinity DataKi:  204nMAssay Description:Inhibition of human uPA using Z-Gly-Gly-Arg-AMC as substrate measured for 15 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529264(CHEMBL4513418)
Affinity DataKi:  956nMAssay Description:Inhibition of mouse uPA using Z-Gly-Gly-Arg-AMC as substrate measured for 15 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529264(CHEMBL4513418)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells incubated for 12 mins by whole cell voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50529264(CHEMBL4513418)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5alpha expressed in HEK293 cells incubated for 10 mins by voltage clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed