BDBM50531924 CHEMBL4464577
SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)CSSC[C@H](NC(=O)CNC1=O)C(O)=O
InChI Key InChIKey=CCJVUWLRIGMAMZ-SZLYCLTDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50531924
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Inhibition of mouse uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of mouse uPA serine protease domain preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Inhibition of human uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human activated protein C preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse thrombin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human plasma kallikrein preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasma kallikrein preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human thrombin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human matriptase preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 2.40nMAssay Description:Binding affinity to mouse uPA by SPR assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 11nMAssay Description:Binding affinity to mouse uPA expressed in HEK2936E cells by ITC assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 24 hrsMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 2 hrsMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured immediatelyMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 8 hrsMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Mus musculus (Mouse))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of the intrinsic peri-cellular uPA in mouse CT26 cells assessed as reduction in cell invasion measured every hour by transwell assayMore data for this Ligand-Target Pair