BDBM50541814 CHEMBL4648848
SMILES C[C@@H]1CN([C@@H](C)CN1C(c1ccc(F)cc1)c1ccccc1F)c1cc(=O)n(C)c2ccc(nc12)C#N
InChI Key InChIKey=QBLJMEHOKNLCLR-VQSPDULUSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50541814
Affinity DataIC50: 580nMAssay Description:Inhibition of full-length C-terminal His6 tagged TVMV-pFBgate fused human DGKalpha expressed in baculovirus infected Sf9 insect cells using liposome ...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of DGKalpha/zeta in human whole blood assessed as induction of T-cell activation by measuring IFNgamma level preincubated for 1 hr followe...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of DGKA/DGKZ in human CD8 cells assessed as induction of CD8 activation by measuring IFNgamma level after 20 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Inhibition of full length C-terminal His6tagged TVMV-His-pFBgate fused human DGK-zeta expressed in baculovirus infected Sf9 insect cells using liposo...More data for this Ligand-Target Pair