BDBM50549381 CHEMBL4784909

SMILES C[C@@H](OCc1ccccc1)[C@H](NC(=O)[C@H](Cc1cccc(Br)c1)NC(=O)c1ccc(cc1)-c1cncnc1)C#N

InChI Key InChIKey=NVLVLDJDOAWDLZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50549381   

TargetCathepsin B(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549381(CHEMBL4784909)
Affinity DataKi:  13nMAssay Description:Inhibition of human cathepsin B using Z-Phe-Arg-AMC fluorogenic peptide as substrate preincubated for 2 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549381(CHEMBL4784909)
Affinity DataKi:  20nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549381(CHEMBL4784909)
Affinity DataKi:  32nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50549381(CHEMBL4784909)
Affinity DataKi:  5.01E+3nMAssay Description:Inhibition of recombinant human cathepsin K using Z-Leu-Arg-AMC as substrate measured after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed