BDBM50550078 CHEMBL4777551

SMILES O[C@]1(CC[C@@H](CC1)N1CCN(Cc2ccc(=O)[nH]c2)CC1)c1cccc(c1)C(F)(F)F

InChI Key

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550078   

TargetTransient receptor potential cation channel subfamily V member 5(Homo sapiens)
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50550078(CHEMBL4777551)
Affinity DataIC50:  560nMAssay Description:Inhibition of human TRPV5 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 6(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50550078(CHEMBL4777551)
Affinity DataIC50:  82nMAssay Description:Inhibition of human TRPV6 expressed in HEK293 cells assessed as reduction in Cd2+ influx by calcium-5 fluorescence dye-based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB