BDBM50555256 CHEMBL4756115

SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](CS)NC(=O)CCNC(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12)C(C)(C)S)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(O)=O)C(C)(C)C

InChI Key

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555256   

TargetGolgi-associated PDZ and coiled-coil motif-containing protein(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555256(CHEMBL4756115)
Affinity DataKd:  113nMAssay Description:Binding affinity to C-terminal His6 tagged CAL PDZ domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence pola...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF2(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555256(CHEMBL4756115)
Affinity DataKd:  4.07E+3nMAssay Description:Binding affinity to NHERF2 PDZ2 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF2(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555256(CHEMBL4756115)
Affinity DataKd:  1.87E+3nMAssay Description:Binding affinity to NHERF2 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50555256(CHEMBL4756115)
Affinity DataKd:  1.64E+3nMAssay Description:Binding affinity to NHERF1 PDZ1 domain (unknown origin) expressed in Escherichia coli BL21 incubated for 1 hr by fluorescence polarization based comp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed