BDBM50588427 CHEMBL5193213

SMILES Cc1cnc(NC2CCOCC2)nc1Oc1ccc(NC(=O)NC2CCN(CC2)c2nnc(-c3ccnn3C)c(C)c2C)cc1

InChI Key InChIKey=QKIRTBZHSZSQET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50588427   

TargetSmoothened homolog(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588427(CHEMBL5193213)
Affinity DataIC50: 150nMAssay Description:Inhibition of SMO in mouse 3T3/HH FlashII-7 cells incubated for 36 hrs in presence of SHH by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed