BDBM50596937 CHEMBL5204071

SMILES COc1ccc(C2NCCc3c2[nH]c2ccc(F)cc32)c(O)c1

InChI Key InChIKey=BLLYZWFUXWXJGP-UHFFFAOYSA-N

Data  12 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50596937   

Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  25nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  50nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  69nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  71nMAssay Description:Binding affinity to 5HT1B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  94nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  110nMAssay Description:Binding affinity to 5HT1D receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  229nMAssay Description:Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  250nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  362nMAssay Description:Binding affinity to D4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity to 5HT1E receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSodium-dependent serotonin transporter(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596937(CHEMBL5204071)
Affinity DataKi:  1.84E+3nMAssay Description:Binding affinity to SERT receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed