BDBM50622715 CHEMBL5431604

SMILES Cc1ncc(c(NC(=O)NC2c3ccccc3-c3ccccc23)n1)-c1ccccc1

InChI Key InChIKey=ZXJYQUGFAQNBBJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50622715   

TargetHigh affinity nerve growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622715(CHEMBL5431604)
Affinity DataIC50: 99nMAssay Description:Inhibition of TRKA (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622715(CHEMBL5431604)
Affinity DataIC50: 99nMAssay Description:Inhibition of human 6-His tagged TRKA expressed in Sf9 insect cells incubated for 2 hrs in presence of ATP by LanthaScreen based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622715(CHEMBL5431604)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of TRKC (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50622715(CHEMBL5431604)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of TRKB (unknown origin) using Kinase substrate 22 pre-incubated with compound for 10 mins followed by substrate and ATP addition measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed