BDBM50634232 CHEMBL5432133

SMILES CC(C)c1nn(CC(=O)Nc2ncccn2)c(=O)cc1-c1cc(F)cc(F)c1

InChI Key InChIKey=VSBTUQVYMIXISB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50634232   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50634232(CHEMBL5432133)
Affinity DataIC50: 289nMAssay Description:Inhibition of NLRP3 in human THP-1 cells assessed as reduction in IL-1beta production measured after 1 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed