BDBM507148 US11046680, Example 19.0::US11046680, Example 20.0::US11046680, Example 21.0

SMILES COCC[C@H]([C@@H](C)c1ncc(F)cn1)S(=O)(=O)Nc1nnc(-c2nc(C)cs2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=WOVUZJAOIKDDTI-DNVCBOLYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 507148   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM507148(US11046680, Example 19.0 | US11046680, Example 20....)
Affinity DataEC50:  6.30nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM507148(US11046680, Example 19.0 | US11046680, Example 20....)
Affinity DataEC50:  90nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM507148(US11046680, Example 19.0 | US11046680, Example 20....)
Affinity DataEC50:  1.10nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent