BDBM507707 N-((1r,4r)-4-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-4-(isopropylamino)pyridin-3-yl)-1,3,4-thiadiazol-2-yl)cyclohexyl)acetamide (Example 24)::US11046686, Example 24::US11702414, Example 24

SMILES CC(C)Nc1cc(ncc1-c1nnc(s1)[C@H]1CC[C@@H](CC1)NC(C)=O)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=SINWNQNTNAGUJM-WGSAOQKQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 507707   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507707(N-((1r,4r)-4-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM507707(N-((1r,4r)-4-(5-(6-(3-cyanopyrrolo[1,2-b]pyridazin...)
Affinity DataIC50: <1nMAssay Description:IRAK4 enzyme (Carna Biosciences, Chuo-ku, Kobe, Japan) activity was measured by detecting phosphorylated peptide substrate formation using an antibod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent