BDBM508718 8-{[1-(2,2-difluoropropyl)azetidin- 3-yl]methyl}-2,2-difluoro[1,3] dioxolo[4,5-h][1,2,4]triazolo[1,5- c]quinazolin-5-amine::US11046714, Example 152

SMILES CC(F)(F)CN1CC(Cc2nc3c4ccc5OC(F)(F)Oc5c4nc(N)n3n2)C1

InChI Key InChIKey=JZINXPBIOZPKGR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508718   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM508718(8-{[1-(2,2-difluoropropyl)azetidin- 3-yl]methyl}-2...)
Affinity DataKi:  5.5nMAssay Description:The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent