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BDBM5143 (5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-pyrrol-2-yl]methylidene}-5H,6H,7H-pyrrolo[2,3-d]pyrimidin-6-one::pyrrolo[2,3-d]pyrimidin-6-one deriv. 28a
SMILES: Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(Nc3ccc4CCCc4c3)c12)C(=O)N1CCOCC1
InChI Key: InChIKey=OZSZUGKQFYJEMK-UHFFFAOYSA-N
Data: 3 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 (Human) | BDBM5143![]() ((5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-meth...) | GoogleScholar | UniChem | n/a | n/a | 3.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Epidermal growth factor receptor (Human) | BDBM5143![]() ((5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-meth...) | GoogleScholar | UniChem | n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Platelet-derived growth factor receptor beta (Human) | BDBM5143![]() ((5Z)-4-(2,3-dihydro-1H-inden-5-ylamino)-5-{[3-meth...) | GoogleScholar | UniChem | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||