BDBM517325 3-[3- (difluoromethoxy)phenyl]- 1-(4-fluorophenyl)-N-(3- methyl-1,1- dioxidotetrahydrothiophen- 3-yl)-1H-indazole-6- carboxamide (enantiomer A)::US11104690, Example 143-A

SMILES C[C@]1(CCS(=O)(=O)C1)NC(=O)c1ccc2c(nn(-c3ccc(F)cc3)c2c1)-c1cccc(OC(F)F)c1

InChI Key InChIKey=XVPLGPINRPQMLZ-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517325   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM517325(3-[3- (difluoromethoxy)phenyl]- 1-(4-fluorophenyl)...)
Affinity DataIC50:  1.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent