BDBM530460 (S)-N-(2-Chloro-6-fluorophenyl)-5-fluoro-4-(3-(2-hydroxypropan-2-yl)-4-methyl-1H-pyrazol-1-yl)-2-((1,1,1-trifluoropropan-2-yl)oxy)benzamide::WO2022070069, Example 3
SMILES C[C@H](Oc1cc(c(F)cc1C(=O)Nc1c(F)cccc1Cl)-n1cc(C)c(n1)C(C)(C)O)C(F)(F)F
InChI Key InChIKey=OIFBFTGIRJTPFV-LBPRGKRZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 530460
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Janssen Biotech
WIPO
Janssen Biotech
WIPO
Affinity DataIC50: 0.5nMAssay Description: To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th...More data for this Ligand-Target Pair