BDBM533972 6-(Azetidin-1-yl)-4-fluoro-N-[3-(propan-2-yl)pyridine-2-sulfonyl]-1-benzofuran-2-carboxamide::WO2022081807, Example 79

SMILES CC(C)c1cccnc1S(=O)(=O)NC(=O)c1cc2c(F)cc(cc2o1)N1CCC1

InChI Key InChIKey=DPJLHLMQQRPZPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533972   

TargetHistone acetyltransferase KAT6B(Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533972(6-(Azetidin-1-yl)-4-fluoro-N-[3-(propan-2-yl)pyrid...)
Affinity DataIC50:  14nMAssay Description:Kat6b inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
The Broad Institute

WIPO
LigandPNGBDBM533972(6-(Azetidin-1-yl)-4-fluoro-N-[3-(propan-2-yl)pyrid...)
Affinity DataIC50:  9.58nMAssay Description:Kat6a inhibitory activities of the compounds described in the present invention were quantified using a Fluorescence Resonance Energy Transfer (TR-FR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed