BDBM5557 2-(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phenyl)acetamide::2-[4-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)phenyl]acetamide::O6-Cyclohexylmethylguanine deriv. 41

SMILES NC(=O)Cc1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1

InChI Key InChIKey=XPEBENJJZXOJBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5557   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5557(2-(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}p...)
Affinity DataIC50:  130nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5557(2-(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}p...)
Affinity DataIC50:  140nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed