BDBM60481 US9079866, 291::US9745328, Compound 291::US9884878, Compound 291

SMILES Nc1ncc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N[C@H](c1ccccc1)C(F)(F)F

InChI Key InChIKey=BPZZDANDHCEDPN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60481   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 60481BDBM60481(US9079866, 291 | US9884878, Compound 291 | US97453...)
Affinity DataKi:  7nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetFlap endonuclease 1(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 60481BDBM60481(US9079866, 291 | US9884878, Compound 291 | US97453...)
Affinity DataKi:  7nMAssay Description:The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2019
Entry Details
US Patent

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 60481BDBM60481(US9079866, 291 | US9884878, Compound 291 | US97453...)
Affinity DataKi:  7nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent