BDBM615945 2-[Bis-(2-fluoro-phenyl)-hydroxy-methyl]-3-ethyl-7-methoxy-imidazo[1,2-a]pyridine-6-carboxylic acid (1-ethyl-1H-pyrazol-4-yl)-amide::US20230271956, Compound 30

SMILES CCc1c(nc2cc(OC)c(cn12)C(=O)Nc1cnn(CC)c1)C(O)(c1ccccc1F)c1ccccc1F

InChI Key InChIKey=DOKWBFNIQHRCSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615945   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 615945BDBM615945(2-[Bis-(2-fluoro-phenyl)-hydroxy-methyl]-3-ethyl-7...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent