BDBM6369 2-[4-(4-Acetyl-piperazin-1-yl)-phenylamino]-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one::8-cyclopentyl-2-{[4-(4-acetylpiperazin-1-yl)phenyl]amino}-5-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Pyrido[2,3-d]pyrimidin-7-one 16

SMILES: CC(=O)N1CCN(CC1)c1ccc(Nc2ncc3c(C)cc(=O)n(C4CCCC4)c3n2)cc1

InChI Key: InChIKey=NWFSVKZROQXYRI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 6369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C] (Human)	BDBM6369 (8-cyclopentyl-2-{[4-(4-acetylpiperazin-1-yl)phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	103	n/a	n/a	n/a	n/a	7.4	25
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM6369 (8-cyclopentyl-2-{[4-(4-acetylpiperazin-1-yl)phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM6369 (8-cyclopentyl-2-{[4-(4-acetylpiperazin-1-yl)phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM6369 (8-cyclopentyl-2-{[4-(4-acetylpiperazin-1-yl)phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair