BDBM7248 (3Z)-4-methyl-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]pyrrol-1-yl}methylidene)-2,3-dihydro-1H-indol-2-one::pyrrollylactone indolinone driv. 15j

SMILES: Cc1cccc2NC(=O)\C(=C/c3[nH]cc4c3CCOC4=O)c12

InChI Key: InChIKey=CTDIFTBJDVQHSA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM7248 ((3Z)-4-methyl-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	7.4	22
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Vascular endothelial growth factor receptor 2 (Human)	BDBM7248 ((3Z)-4-methyl-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	25
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Platelet-derived growth factor receptor beta (Human)	BDBM7248 ((3Z)-4-methyl-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	25
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM7248 ((3Z)-4-methyl-3-({4-oxo-2H,4H,6H,7H-pyrano[3,4-c]p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	25
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					More data for this Ligand-Target Pair