BDBM7384 2-phenyl-1H-pyrrolo[2,3-b]quinoxaline::Aloisine-Related Compound 7

SMILES c1c([nH]c2nc3ccccc3nc12)-c1ccccc1

InChI Key InChIKey=JYNNROJYCARHFN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7384   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7384(2-phenyl-1H-pyrrolo[2,3-b]quinoxaline | Aloisine-R...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7384(2-phenyl-1H-pyrrolo[2,3-b]quinoxaline | Aloisine-R...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Rat)
Faculte De Medecine Et De Pharmacie

LigandPNGBDBM7384(2-phenyl-1H-pyrrolo[2,3-b]quinoxaline | Aloisine-R...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2006
Entry Details Article
PubMed